Research Articles
GMP Standards for Clinical-Grade MSC-EV Production: A Comprehensive Guide for Researchers and Biotech Professionals
This article provides a comprehensive, up-to-date guide to Good Manufacturing Practice (GMP) standards for producing Mesenchymal Stromal Cell-derived Extracellular Vesicles (MSC-EVs) for clinical applications.
A Comprehensive Guide to GMP-Compliant Neural Progenitor Differentiation from Human Embryonic Stem Cells
This guide provides a detailed roadmap for researchers and industry professionals aiming to differentiate human embryonic stem cells (hESCs) into neural progenitors under Good Manufacturing Practice (GMP) conditions.
Ensuring Clinical Safety: GMP Strategies for Tumor-Free Pluripotent Stem Cell Manufacturing
This article provides a comprehensive guide to Good Manufacturing Practice (GMP) processes specifically designed to eliminate tumorigenic risk in pluripotent stem cell (PSC) therapies.
Potency by Design: A GMP-Compliant Roadmap for MSC Assay Development in Cell Therapy
This article provides a comprehensive guide for researchers, scientists, and drug development professionals on establishing robust, Good Manufacturing Practice (GMP)-compliant potency assays for Mesenchymal Stromal/Stem Cells (MSCs).
GMP-Compliant Enzymatic Digestion for MSC Isolation: A Complete Protocol Guide for Clinical Translation
This comprehensive guide details the critical process of isolating Mesenchymal Stem Cells (MSCs) using GMP-compliant enzymatic digestion.
GMP Cleanroom Classification for Cell Therapy: Standards, Implementation & Validation Guide 2024
This definitive guide for researchers, scientists, and drug development professionals explores the critical role of GMP cleanroom classification in cell therapy manufacturing.
Choosing the Right ESC Culture Medium: A 2024 Comparative Guide for Stem Cell Researchers
This article provides a comprehensive, up-to-date functional comparison of embryonic stem cell (ESC) culture media formulations.
The FoxO Pathway: Unlocking the Secrets of Genuine Stem Cell Quiescence in Regeneration and Disease
This comprehensive review synthesizes current research on the critical role of FoxO transcription factors in establishing, maintaining, and reactivating genuine quiescence in adult stem cell pools.
The Definitive Guide to Flow Cytometry Potency Assays for MSC Therapies: From Validation to Clinical Release
This comprehensive guide provides researchers and drug development professionals with an in-depth analysis of flow cytometry-based potency assays for Mesenchymal Stromal/Stem Cells (MSCs).
Feeder-Free Human ESC Culture: Protocols, Matrices & Media for Defined Conditions in 2024
This comprehensive guide explores feeder-free culture systems for human embryonic stem cells (hESCs), addressing key needs of researchers and drug developers.